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Of the more than 100 cannabinoids in the cannabis plant, tetrahydrocannabinol (THC) is the one principally responsible for the psychoactive and intoxicating effects of cannabis consumption.

Live cannabis plants contain tetrahydrocannabinolic acid (THCA), the non-active version of this compound. When cannabis is decarboxylated through heating to a high temperature, drying or curing, the acid molecule (the “A” in THCA) drops off, and the THC is activated. This results in the effects we associate with consuming THC. It also means that cannabis in its fresh form is not yet active with THC.

How THC Works

THC interacts with the body’s endocannabinoid system (ECS). Studies suggest this system plays a role in regulating stress recovery, protecting our nervous system, activating our immune system response and regulating our homeostatic balance (our overall state of optimal health, function and stability).

Put simply, your ECS is made up of two things:
  1. Cannabinoid receptors, present in nearly every region of your central nervous system and brain, as well as many other areas of the body, including your immune system; and
  2. Cannabinoids that you naturally produce (called endocannabinoids).

Your natural endocannabinoids fit into your ECS receptors like a key in a lock and help carry messages from cell to cell. THC works the same way, temporarily replacing your own endocannabinoids, but with different effects. These may include:

    • The release of dopamine, resulting in feelings of relaxation;
    • A physical response, such as reduced inflammation or an increase in hunger; and
    • Effects on various regions of the brain, including the hippocampus (memory), the frontal cortex (thinking and decision-making) and the cerebellum (physical movement and coordination).
    • Indica strains are believed to be physically sedating, perfect for relaxing with a movie or as a nightcap before bed.
    • Sativas are said to provide invigorating, uplifting cerebral effects that pair well with physical activity, social gatherings, and creative projects.
    • Hybrids are thought to fall somewhere in between, offering a balance of indica and sativa effects.

 

This belief that indicas, sativas, and hybrids deliver distinct effects is so deeply rooted in mainstream cannabis culture that budtenders typically begin their strain recommendations by asking you which of these three types you prefer.

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While cannabis producers may link the use of their products to specific desired effects, such as energy, calm, sleepiness or hunger, these claims have not been backed by substantiated scientific studies.

How Will Cannabis Affect Me
HIGHLIGHTS
  • Cannabis effects depend on many factors, such as your genetic makeup, frequency of use, age, sex, current mood and personality, and any existing mental health conditions.
  • Customers should do their own unbiased research when shopping for and choosing cannabis products

Looking for a cannabis strain that will give you energy? Make you sleepy? Read on to learn what the research says about cannabis and its effects before you shop.

How will I know how it will affect me?

Humans and cannabis plants share similar chemical compounds called cannabinoids (in people, they’re known as endocannabinoids). We produce them naturally through our endocannabinoid system, which is thought to control how we feel, move and react. We also have cannabinoid receptor sites all over our bodies, which the endocannabinoids bind to. The plant’s cannabinoids — the most studied of which are tetrahydrocannabinol (THC) and cannabidiol (CBD) — also interact with these receptors and inhibit the way they function. To learn more about the endocannabinoid system, click here.

Because the number of receptors and their locations vary from person to person, our reactions to THC and CBD differ as well. So even if two people consume the exact same strain of cannabis, their reactions and the effects could be very different. The effects of cannabis also depend on factors such as the consumption method and frequency of use, and your genetics, age, sex, personality, current mood and existing mental health conditions.

What does the research say?

Although consumers have reported that cannabis may have health benefits and effects, pleasant or not, the small amount of research conducted to date does not adequately back up these mostly anecdotal claims.

Besides THC and CBD, there are hundreds of compounds present in cannabis. However, to date, researchers have been unable to do adequate research into how it works and its effects on the body.

So where do I find unbiased information?

While many Licensed Producers give intended or reported effects for their products, this information is often crowd-sourced from the consumers who have used them. The effects have generally not been scientifically gathered or tested.

Read up on the latest research by checking out neutral sources, such as the Government of Canada website, as well as the Learn section of OCS.ca.

Ultimately, the best way to know how cannabis will affect you is through personal experience. Begin with a product that is lower in THC and CBD potency, and use a small amount to see how it affects you.

  • Indica strains are believed to be physically sedating, perfect for relaxing with a movie or as a nightcap before bed.
  • Sativas are said to provide invigorating, uplifting cerebral effects that pair well with physical activity, social gatherings, and creative projects.
  • Hybrids are thought to fall somewhere in between, offering a balance of indica and sativa effects.

This belief that indicas, sativas, and hybrids deliver distinct effects is so deeply rooted in mainstream cannabis culture that budtenders typically begin their strain recommendations by asking you which of these three types you prefer.

Continue Reading

When browsing cannabis strains or purchasing cannabis at a shop, you may notice strains are commonly broken up into three distinct groups: indica, sativa, and hybrid. Most consumers have used these familiar cannabis types (indica vs. sativa) as a touchstone for predicting effects:

  • Indica strains are believed to be physically sedating, perfect for relaxing with a movie or as a nightcap before bed.
  • Sativas are said to provide invigorating, uplifting cerebral effects that pair well with physical activity, social gatherings, and creative projects.
  • Hybrids are thought to fall somewhere in between, offering a balance of indica and sativa effects.

This belief that indicas, sativas, and hybrids deliver distinct effects is so deeply rooted in mainstream cannabis culture that budtenders typically begin their strain recommendations by asking you which of these three types you prefer.

Indica vs Sativa

Continue Reading
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